Seussical centers around Horton the Elephant, who finds himself faced with a double challenge: Not only must he protect his tiny friend, Jojo, (and all the invisible Whos), from a world of naysayers and dangers, but he must guard an abandoned egg, left to his care by the irresponsible Mayzie La Bird. Although Horton faces ridicule, danger, kidnapping and a trial, the intrepid Gertrude McFuzz never loses faith in him.